(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-furan-2-ylpropanoate - Names and Identifiers
(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-furan-2-ylpropanoate - Physico-chemical Properties
Molecular Formula | C22H19NO5
|
Molar Mass | 377.39 |
Density | 1.318 |
Melting Point | 129.7 °C |
Boling Point | 505.72°C (rough estimate) |
Flash Point | 318.6°C |
Solubility | DMSO (Slightly), Methanol (Slightly) |
Vapor Presure | 2.1E-15mmHg at 25°C |
Appearance | Solid |
Color | White to Off-White |
pKa | 3.62±0.10(Predicted) |
Storage Condition | Sealed in dry,2-8°C |
Refractive Index | 1.5614 (estimate) |
Physical and Chemical Properties | Storage Conditions: 2-8 ℃ WGK Germany:3 |
(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-furan-2-ylpropanoate - Risk and Safety
Hazard Symbols | Xi - Irritant
|
Safety Description | S22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
|
WGK Germany | 3 |
(2S)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-furan-2-ylpropanoate - Introduction
Fmoc-L-2-Furylalanine, also known as methyl fluorene Ester alanine Ester, is an organic compound. The following is a description of its nature, use, preparation and safety information:
Nature:
Fmoc-L-2-Furylalanine is a white solid with a chemical formula of C15H15ClNO5 and a molecular weight of 327.74g/mol. It has high thermal stability and solubility.
Use:
This compound is often used as a pharmaceutical intermediate, especially in the synthesis of anti-inflammatory drugs. It can also be used as an additive to aid in the solubility of the drug.
Method:
The synthesis of Fmoc-L-2-Furylalanine is usually accomplished by chemical reactions. The specific preparation method may include esterification reaction, aminolysis reaction and substitution reaction.
Safety Information:
For the safety of this compound, general laboratory safety regulations need to be followed. It may cause irritation and damage to the eyes, skin and respiratory tract, so it is necessary to wear appropriate personal protective equipment, such as safety glasses, protective gloves and respirators. In addition, inhalation or contact with the compound should be avoided. If necessary, operate in a well-ventilated area, and properly handle and store the compound.
Last Update:2024-04-09 20:52:54